Archives: Grants

Robert A. Hill, Ph.D., Dartmouth College

Mechanisms of Myelin Degeneration and Clearance in the Live Brain

A complex cell structure called myelin has evolved to speed up and finely tune the transmission of electrical signals in the brain. In numerous human diseases, myelin is damaged and must be removed before tissue repair can occur.

Kai Miller, M.D., Ph.D., Mayo Clinic

An Implanted Brain-computer Interface for ALS Patients

Implanted brain-computer interfaces (BCls) recently made the jump from a tool requiring a custom hardware setup at the bedside and the full-time assistance of a scientist, to a small off-the-shelf implant that can be used independently to control programs on a tablet without assistance.

Ikuko Smith, Ph.D., University of California, Santa Barbara

Active dendritic processing of sensory inputs in vivo

During sensory perception, neural circuitry processes information by filtering, amplifying, and integrating electrical signals. The proposed project focuses on uncovering the underpinnings of such processes using electrophysiology, brain imaging, and behavioral analyses.

Kathleen Smith, Ph.D., University of Colorado, Denver

Excitatory and inhibitory synapse communication in synaptic plasticity

During many neurological diseases, brain regions that are essential for learning and memory become over-excitable, due to excessive nerve impulses between nerve cells. This causes nerve cells in these regions to behave abnormally or die, leading to brain damage.

Megan Williams, Ph.D., University of Utah

A New Class of Autism-associated GABA Neurons in Memory Precision

The proper function of the brain requires the concerted action of billions of interconnected brain cells called neurons. Most neurons are excitatory and their activation releases glutamate, which increases brain activity. However, some are inhibitory and their activation releases GABA, which decr...

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