Seed Grants

Founded in 1981, BRF’s Seed Grant Program provides start-up funds for new and innovative research projects that lead to future opportunities, collaboration, and scientific advancement.

Seed Grant Guidelines 

BRF funds the most innovative and high-impact brain research projects. The 2022 Seed Grant Letter of Intent round will open in early October. To learn more about our application guidelines for the Seed Grant, click below.

Seed Grants Archive

Brain Research Foundation The role of microglial lysosomes in selective neuronal vulnerability
Synapses, the sites of signaling between neurons in the brain, play essential roles in learning, memory, and the health of neurons themselves. An enduring mystery is why some neurons are…
Brain Research Foundation How the nervous system constructs internal models of the external world
As animals navigate their environments, they construct internal models of the external sensory world and use these models to guide their behavior. This ability to incorporate ongoing sensory stimuli into…
Brain Research Foundation When Neural Circuits Meet Molecular Circuits: Quantitative Genetic Manipulation with Single-cell Consistency
Cells are the building blocks of our bodies. We get sick when the cells “misbehave”. The way modern gene therapies work is to introduce genes, fragments of DNA molecules that…
Brain Research Foundation Conducting the orchestra of movement—functional role of striatal astrocytes in health and disease
Movement requires coordinated activity across a large brain-wide network. The striatum is a particularly important part of this circuit; it integrates motor-related information from many distinct brain regions to regulate…
Brain Research Foundation Rethinking Remyelination: The role of mature oligodendrocytes in remyelination
Can the adult brain regenerate? Finding the answer to this question is an overarching goal of the field of neuroscience.
Brain Research Foundation Decoding Speech from Electrocorticography
Losing the ability to speak can be devastating. Sometimes, though, people lose this ability without losing the ability to plan the proper mouth movements for speaking.
Brain Research Foundation A zebrafish model to study microglial-extracellular matrix dynamics during synapse development
The connections between nerve cells- called synapses- are essential for all brain functions, including thinking, behavior, and movement. Impaired development of these synaptic connections can contribute to disorders like autism…
Apply for a Grant

Brain Research Foundation invites eligible U.S. institutions to nominate one faculty member to submit a letter of intent for the Fay/Frank Seed Grant Program. To be eligible, the Principal Investigator (PI) must be a full-time assistant or associate professor working in the field of neuroscience.

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